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Organic Sulfur Crystals

99.9% Pure, Premium, Therapeutic, MSM Supplement

by Happy Body.

New 1 Pack Pound of Organic Sulfur Crystals

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Organic Sulfur Crystals.

Organic Sulfur Crystals are what you need in a world where our bodies are constantly bombarded with pesticides, chemical fertilizers, over-processed foods, GMO’s, dangerous heavy metals and significant environmental toxins.

As such, you should really consider supplementing with a 99% Pure, Therapeutic-Grade, Premium, Dietary MSM Supplement in the form of Organic Sulfur Crystals. This form of MSM is pure, and the most potent and highly absorbable type of MSM – by far.

Of note, there are only a few, true sources of 3rd party, independently certified, Pure MSM on the market, of which we are one. Happy Body strives to provide the highest quality, fully bio-active organic sulfur, in the rapidly absorbed crystal format.

But in the end, regardless of where you buy your MSM from, we hope you always choose crystals over all other forms of MSM, as you will see the best, most optimal results for your body and health.

Supplementing with Happy Body Organic Sulfur helps provide your body with the critical ability to quickly limit brutal, chronic pain, inflammation, function much better, eliminate toxins, and keep hair, skin and nails looking amazing, plus so much more…

We used to get adequate bio-active sulfur from our food, but due to commercial over-farming, and growing methods, this key mineral that our body depends on for so much, is now basically gone from dietary sources. This is why so many are experiencing chronic pain and poor wellness today.

Today, 1 in 3 North Americans are in poor health or suffer from severe Chronic Pain (Source: the CDC). Today, your health, well-being and ability to cope is completely in your hands, and by supplementing with Pure Organic Sulfur Crystals, you give your body a massive advantage in dealing these issues naturally.

You can see more on Organic Sulfur Crystals below, including reviews and FAQ’s below.

Buy Organic Sulfur Crystals

99.9% Pure, Premium, & Therapeutic-Grade.

check-box-30x30  No Fillers, No Additives. No GMO’s & 100% Gluten Free.

check-box-30x30 Each Batch Certified Pure By Independent Lab Testing.

check-box-30x30 Free Shipping, Fast Delivery 3 – 5 Business Days.

check-box-30x30 Amazing For Pain, Fatigue, Appearance & Much More.

check-box-30x30 100% No Time Limit Return Policy.

Always Great To Share With Family, Friends and Pets.
Front Product Organic Sulfur Crystals MSM Supplement 600x578

1 LBS (454 Gram) Bag.

Provides a 30 – 90 Day Supply Based on Dosage Size.


Rating: 4.83 Stars Out of 5.

Regular Price: $49.99

Our Price:

$34.99 + Free Shipping

That’s 30% Off! 

Add To Cart 2016-10-26_14-34-57

Buy In Bulk & Save Even More.

Supplemental Facts happy body organic sulfur benefits


Organic Sulfur Crystal Benefits.

– 99.9% Pure Organic Sulfur Crystals (distilled) in a 1 LBS foil resealable pouch.
– Excellent for: body pain, inflammation, detoxification, leaky gut, circulation, hair, skin and nails.
– Provides cellular oxygenation and blood circulation.
– Helps reduce fatigue, increase energy, focus and ability to concentrate.
– Helps replenish keratin for thicker hair follicles, and faster hair growth.
– Makes skin much more flexible and softer. Significantly helps with wrinkles and scar tissue.
– Excellent for skin conditions like eczema, rashes, rosacea, and acne.
– Greatly reduces allergies, headaches and migraines.
– Potent amino acid, antioxidant and enzyme support.
– Helps improve nutrient absorption, and remove toxic waste from your cells.
– Helps to control stomach acidity, ease constipation and reduce parasites in the body.

Purity & Quality Guaranteed.

Quality Pure MSM

– 99.9 Pure MSM, Therapeutic Grade Organic Sulfur Supplement.
– Made in small, quality controlled batches in an FDA Registered Facility.
– 3rd Party Laboratory Tested, and Verified For Absolute Purity and Quality.
– Simple To Use: 1 spoonful morning and night.
– Vegan Friendly. 100% Gluten Free. 100% Sugar free. 100% GMO Free. 100% Dairy Free.
– Therapeutic-Grade, Pure, Distilled MSM with No Additives.
– Highest Concentration of MSM / Sulfur available on the market.
– No fillers, flow agents, binders, anti-caking agents or preservatives.
– No Plastic or BPA Packaging.

Easily The Best Value.


5 Star Customer Service:

Organic Sulfur Customer Reviews

Trust 4

What Is Organic Sulfur?

Organic Sulfur is the pure crystal version of the organo-sulfur compound MSM, (scientific name Methyl/Sulfonyl/Methane). MSM is a critical, fully bio-active mineral supplement needed by the body for a vast number of very beneficial things.

Your muscles, joints, cartilage, skin, hair, and much more in your body, depend on organic sulfur for proper and optimal function.

Organic Sulfur’s value as a dietary supplement began with the research of Stanley Jacob MD, a medical researcher at the University of Oregon. His research documented the significant therapeutic benefits to more than 15,000 subjects and patients.

The results of his research were so impressive that Dr. Jacob felt compelled to write a book called a bestselling book called “The Miracle of MSM”.

MSM is proven highly effective for:

– Arthritis, Inflammation, Gout and Chronic Pain (we also carry a version for dogs too).

– Fibromyalgia and Lupus symptoms.

– Toxin, heavy metal, lactic acid, and parasite removal from the body.

– Allergy,  headache / migraine relief.

– Skin beautification, and vastly improving conditions like: eczema, rashes and scars.

– Helping stop thinning hair and brittle, poor-growing finger nails.

So much more…

Why Are We Deficient in Organic Sulfur?

Many studies show that we are in the midst of a silent epidemic here in North America; whereby our population is in a state of mass organic sulfur deficiency.

This is directly due to the soil we use to grow our food, which has been rapidly depleted of its nutrients, and crucial mineral base, especially sulfur.

Note: the only place you can get organic sulfur from is from your food (or high quality supplements). Your body can’t make its own organic sulfur.

Minerals enter the body through our food from soil

Again, the reason our soil has lost much of its sulfur and key mineral base, is due to the massive overuse of commercial farming techniques, chemical fertilizers and pesticides.Key mineral depletion in soil

This is not a theory. The US Department of Agriculture has confirmed this through a large scale study.

The Decline in Organic Sulfur In North America:

(And Other Minerals) Over the Past 100 Years.Drop in organic sulfur and other minerals in our soil

Source: USDA data from 1963, and 1997. Our data extrapolation and projections after 2006 are based on USDA data, including Hamaker 1982.

Minerals like Organic Sulfur, Magnesium, Copper,  Selenium, and Zinc have dropped to just a fraction of what they were at just 60 years ago, due primarily to our current farming methods.

The net result is our food simply does not have the nutritional content as it used to just 100 years ago.

The Difference in our soil and food today.

Soil contents

What Happens When You’re Low On Organic Sulfur?

When your body does not get enough organic sulfur the following can typically happen:

  • Significant increase in pain and inflammation.
  • Lack of mobility, and loss of ability to things you used to be able to do.
  • Massive buildup of toxins, heavy metals, and acids in your system.
  • Growth of parasitic organisms in stomach and intestines.
  • Thinning hair and hair loss + brittle, weak nails.
  • Skin roughness, blotchiness, and poor complexion.
  • Lack of energy and fatigue.
  • Depression and poor blood circulation.
  • Poor liver function and toxic liver.
  • Symptoms of premature aging.

Minerals Go Down as Diseases Go Up

The lack of dietary minerals in our food, is also evident in the significant growth of disease and chronic pain conditions over the past 100+ years, as seen by this chart. 

Organic Sulfur and other minerals go down, as disease increases.

Source: Data Visualization derived from data sets via USDA, CDC, NIH, NCHS and the AHA.

Organic Sulfur is Simply a MUST Today

From our water to our food, to our homes and work environments, we are bombarded daily with chemicals, toxins and heavy metals.

Toxins in the environment are removed from the body by Organic Sulfur MSMOur water supply is also a significant source of heavy metals across the US, as what is being revealed today in Flint Michigan. This is also the case throughout much of the USA and Canada.

Organic Sulfur is critical for detoxification from common sources

Summary of Organic Sulfur Benefits.

The benefits of using a Pure, Premium, Therapeutic Grade Organic Sulfur Crystals MSM daily include:

  • Significant body pain and inflammation relief.
  • Impressive reduction of headaches and migraines.
  • Deep cellular, whole-body detoxification.
  • Large Increases in energy and mental clarity.
  • Greatly improved blood circulation and oxygenation of blood cells.
  • Vastly improved feelings of general wellness and immune booster.
  • Thicker, fuller, stronger hair follicles.
  • Significant reductions with eczema, acne and blotchy skin conditions.
  • Reductions in Leaky Gut, Diverticulitis, Parasites, and Intestinal Issues.
  • Increases the efficiency of core vitamins C, B, D and magnesium.

The Best Organic Sulfur / MSM

Happy Body Organic Sulfur is certified 99.9% Pure MSM with no additives. Each batch we sell is third-party tested for purity, and quality by Certified Labs in Los Angeles, a fully FDA complaint food and vitamin testing lab.

Many of the lower cost MSM products in Walmart, Amazon and local health food stores are made off-shore with no 3rd party testing.Most Store Bought MSM

MSM Pills & Powders Don’t Work Well.

Organic Sulfur Versus Other Forms of MSM

Regardless where you buy from, pills and powdered versions of MSM are not as effective as Therapeutic Grade Pure Organic Sulfur Crystals.

Pills can typically be mixed with other fillers lowering the quantity and quality of the MSM / Sulfur content. Powders can be mixed with anti-caking agents, and significantly reduce the ability for your body to absorb the product.

Organic Sulfur Crystals / MSM Supplement Comparison Chart:

Crystals Versus Powders and Pills

Organic Sulfur Crystals Comparison Chart

How To Take Organic Sulfur Crystals.

MSM Supplementation made easy

Our clients start with anywhere between a 1/4 teaspoon –  to – 1 teaspoon, 2 x daily (morning and early evening. It’s best to take Organic Sulfur Crystals with filtered or distilled water, or a small amount of juice. Or as directed by your health practitioner.

We also suggest to always use filtered or non-chlorinated water, and not take with medication, as these can also destroy or interfere with the Sulfur’s effectiveness.

Of note, Organic Sulfur has a mild blood-thinning effect, so if you are already on blood thinners like Coumadin or Warfarin, you should always consult your doctor before use.

Remember to read our label for all directions and suggestions on use, and if you still have more questions or concerns always talk to your health practitioner.

Who Should Use Organic Sulfur?

Really, everyone should be using Organic Sulfur, even pets, as our society is very low in organic sulfur. Specifically, you should really consider therapeutic grade Organic Sulfur if you have:

  • Arthritis, Bursitis
  • Chronic Joint issues (knee, tennis elbow, hand, shoulder or carpal tunnel).
  • Chronic neck back and muscle pain.
  • Tendinitis, Plantar Fasciitis, or Sciatica.
  • Hair Issues (Thinning or weak, brittle hair, grey hair).
  • Skin Issues (Eczema, dry skin or acne and blemished).
  • Blood flow and circulation.
  • High blood pressure (see your doctor first if you use blood thinners).
  • Toxic liver or blood.
  • Low energy poor general health.

Thanks for reading more on Organic Sulfur, we offer fast, free shipping and a great sales price. You can also save more on our bulk packs.

Organic Sulfur Reviews

Have a review for us? Leave A Review!

Average rating:  
 223 reviews
by Stephanie L on Organic Sulfur Crystals
Love using this!

Wonderful product!!

by Barb Conter on Organic Sulfur Crystals
So far, so good!

I have been using the sulfur crystals for about a month and feel like they are doing what they are supposed to do. I have arthritis in my knee and I'm hoping that it will help to renew the cartilage. I am ordering again.

by Audra Moore on Organic Sulfur Crystals
What can I say!?

Ok, I was skeptical, saw the info and reviews, had heard good things about the company so thought ok lets try it. Arrived very fast, great info on how to use it. The taste is bitter for sure but not at all terrible. About 3 weeks in all I can say is WOW, my pain level has gone from a 10 to a 2 or 4 on really bad days, its amazing, I feel better, I look better, I sleep so much better it really is life changing. Thank you for this awesome product.

by Debbie Houston on Organic Sulfur Crystals
Good so far!

I'm on 3rd week of using sulfur crystals my back pain is minimal, i have cataracts and have blurred vision noticed an improvement already!

by Cheryl Reeves on Organic Sulfur Crystals
OMG a miracle!

I was very leary of trying but thank God I did, within 3 wks I no longer needed my cane to walk. I couldn't walk anywhere without it.Both knees have been replaced and I'm double rodded from S1-T4, 14 levels, my 3rd back surgery. I couldn't bend my knees due to the fusion so putting on pants, shoes, sox impossible.Now I can bend my knees enough to get my pants, shoes n sox on.  I haven't had this much energy in 20yrs.I'm 70 n I figured in another year I would b in a wheelchair, not anymore, unbelievable product.I also have skin cancer on my arms n legs n the scaly things that are going away on my arms haven't looked this good in 40yrs.My legs have improved by 50% and still improving. The swelling in my knees and knuckles are gone and my hands working much better too. My face is smooth and my significant other says I definitely look younger, from him that's a compliment.My hair getting thick and my nails aren't breaking. I'm a believer because it actually works better then I could have imagined. Thank you for giving me my life back.

by Nicole Anderson on Organic Sulfur Crystals
Incredible Results !!

I ordered the Organic Sulfur Crystals after seeing an interview with Dr. Mercola in Nov. I had been suffering with horrible deep tissue pain for 5 months with only 2-4 hours of sleep a night. After only 4 days the pain was gone. It was more than I could have hoped for. In addition within that same time frame a spot on my face that I could not get rid of, (after 2 rounds of antibiotics and a trip to the dermatologist ) reduced by half and went away totally in a week. Nice bonus benefits are that my skin is baby soft and my hair and nails are growing very fast. I am convinced that much of the degenerative diseases are due largely to the missing nutrients that are no longer in our fruits and vegetables. Thank you Happy Body for a restful sleep and a flawless face!!!! 🙂

by Cindy Umfress on Organic Sulfur Crystals
Great product

Sulphur crystals have greatly alleviated my knee pain!

by LOUTRICIA JONES on Organic Sulfur Crystals
Lupus Relief!

Suffering from lupus and all the pain and problems that come with it keeps me busy looking for relief. I thought I had tried every alternative treatment that exist. For Christmas I decided to treat myself and my daughter to a bag of MSM from Happy Body Store. I could give lots of details, including the names of the prescription drugs that I no longer need, but a better review would be to say that I have just placed another order for us both. So, so thankful for this find.

by Mary McCandlis on Organic Sulfur Crystals
Feeling Excellent!

Been taking it since mid December, and really after 7 days started to feel relief from my horrible shoulder and neck pain, and now seeing a difference in my knees. Have also seen real changes in my energy levels. Very happy to have found this product a good friend shared with me on Facebook. It's got a bitter taste but it goes away in a few seconds, do not let that stop you from trying this as its the first product I have found to actually do what it says it can do...

by Sandy Cooper on Organic Sulfur Crystals
A real difference maker so far.

I use Organic Sulfur and Turmeric, and so far after 3 weeks Im noticing a real reduction in pain, its been transformative to say the least. Have to say my skin has not looked this good since Reagan was in office lol.

by Joan Blais on Organic Sulfur Crystals
Good Stuff

Big difference in pain level in just 3 weeks - good stuff!

by Kathy Smith on Organic Sulfur Crystals
I'm a believer.

After reading reviews for about a year, I finally ordered a bag of Happy Body MSM. I have been using this product for 1 month. Have noticed less neuropathy in my feet and much more flexibility. More energy and mood improvement, too. Mixing it with 6 ounces of room temp water. Taste is not the best- but for those few seconds the offset of pain reduction all day is so worth it.

by Maria Lopez on Organic Sulfur Crystals
Great Stuff!

My joint pain is GONE! I have more energy. Hair is growing again - menopause had virtually stopped the growth.

by Karen Oelberg on Organic Sulfur Crystals
5 star product!

We have been using organic sulfur for 2 months. Have noticed no more pain. The sulfur is rebuilding joints like promised. Hair is softer and skin is soft. Very happy with this product.

Wow! Excellent product!

Very pleased with this product. Dissolves well in warm water. Aches and pains are at a minimum. Nails and hair growing fast! Highly recommend this product!

by Sylvie Hipp on Organic Sulfur Crystals

Started taking the sulfur 3 weeks ago and already feel a positive change, more energy and also motivation, less procrastination doing chores. Eyesight is better (use readers less) sleep better, skin and hair already look better. I started with (2) teaspoons but I am now (1) a day it seems to work better for me.

by Jean Broker on Organic Sulfur Crystals
Great results!!

Had almost immediate results. Biggest change was in my sleep pattern. Used to wake in the night with aches and pain. After starting the Sulfur crystals, I sleep through the night and do not wake in the morning with stiffness. My mental well being has improved due to the physical improvement. Will continue to use without question.

by Barb Bentree on Organic Sulfur Crystals
Going as planned. Will update later.

Have not used that long only 2 days, but delivery was very fast, and when I had a few questions for customer service, the person I spoke to was excellent. The taste is marginally bitter but goes away fast,  will update this once I have tried for longer.

by Jane Lovell on Organic Sulfur Crystals
Organic sulfur wellness

I have been taking the organic sulfur for about a month now. I do not mind the bitter taste at all any more. I have a lot more energy and the pain in my wrist and hips is much better. It took a few weeks to get over the initial detox headaches but they are gone now. The only problem I have with the sulfur is not being able to sleep taking it twice a day. I now take the full dose in the morning and that is getting better. The sense of overall wellness is awesome.

by Elizabeth Larson on Organic Sulfur Crystals
Great Energy and more.

I've been taking organic sulfur for about 3 weeks and notice a huge difference in stamina and motivation. It was recommended to me to help me to continue my healing from mold toxicity and all of the ailments that came as a result of that. I am starting to feel 'normal' and have much clearer thinking, more energy and sleep much better! My leg cramps have gone away as well. I love it so much I gave it to my sister for Christmas!

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Buy Organic Sulfur Crystals

99.9% Pure, Premium, & Therapeutic-Grade.

check-box-30x30  No Fillers, No Additives. No GMO’s & 100% Gluten Free.

check-box-30x30 Each Batch Certified Pure By Independent Lab Testing.

check-box-30x30 Free Shipping, Fast Delivery 3 – 5 Business Days.

check-box-30x30 Amazing For Pain, Fatigue, Appearance & Much More.

check-box-30x30 100% No Time Limit Return Policy.

Always Great To Share With Family, Friends and Pets.
Front Product Organic Sulfur Crystals MSM Supplement 600x578

1 LBS (454 Gram) Bag.

Provides a 30 – 90 Day Supply Based on Dosage Size.


Rating: 4.83 Stars Out of 5.

Regular Price: $49.99

Our Price:

$34.99 + Free Shipping

That’s 30% Off! 

Add To Cart 2016-10-26_14-34-57

Buy In Bulk & Save Even More.

Supplemental Facts happy body organic sulfur benefits

Organic Sulfur FAQ’s

Q: What is Organic Sulfur?

A: Organic Sulfur is a food-grade, dietary bio-active mineral supplement. High quality, therapeutic-grade Organic Sulfur is always 99.9% pure MSM, with no additives, and in crystal form for so your body can absorb it best.

Q: Why is Organic Sulfur good for pain management and wellness?

A: Organic Sulfur in its crystal form, provides a therapeutic dose of MSM that is highly effective for:

  • Chronic Pain and Inflammation Throughout the Body.
  • Lack of Energy, Clarity and Focus.
  • Body Toxicity.
  • Poor Skin, Hair and Nails.
  • Increased Mobility and range of motion.
  • Blood circulation, supporting liver function.
  • Increasing energy, stamina, focus and ability to concentrate.
  • Thickening hair follicles, and reduce hair thinning.
  • More flexible and softer, helps to reduce wrinkles and scar tissue.
  • Reducing allergies and headaches / migraines.
  • Helping to convert carbs into energy.
  • Promoting normalized enzyme and amino acid function.
  • Improving nutrient absorption, helps controls stomach acidity, eases constipation and reduces parasites in your system.

Q: How long does it take to start working?

A: For many of our clients, the results can happen as early as a few days. More often, results are seen in 2 – 5 weeks.

Q: Is it really easy to take?

A: Yes. It’s very simple, you take 1/4 to 1 level teaspoon of the crystals and add it to a small glass, add 1 ounce of filtered water or juice (filtered water is preferred).

Swirl the glass around, as the crystals do not dissolve fast (that is because they are pure). Once the crystals are moving in a circular motion in the glass, drink it back and your done! You do that 2 x a day, in the morning, and once at early evening.

Note: Sulfur can give you energy, so its best to take the 2nd dose in the later afternoon or early evening.

Also Organic Sulfur has a bitter taste that goes away very fast. You can use juice to easily mask the bitterness or use a splash of fresh Lime which removes any bitterness.

Q: How long does a 1 Pound Pouch last?

A: The 1 LBS bag is enough for 30 – 90 days supply depending on need. If you want to do this with a partner, friend or loved one, we also offer bulk packs where you can save a lot more per bag. You can also use Organic Sulfur for your pets.

Q: Who is Happy Body Store?

A: We are a small, specialized online retailer that focuses on natural ways to heal our bodies from Chronic pain, external toxins and nutrient deficiencies. We are committed to quality, results and 5-star customer service. Our products are made in an FDA registered facility.

All testing is done 2x per batch. Once by our lab, then again by a 3rd Party lab that’s FDA registered as well – Certified Laboratories in California.

Each batch is tested for purity. 99.9% is the minimum we accept. We also test against heavy metals and contaminants for ultimate quality and purity. We offer a 100% customer satisfaction, no time limit guarantee because we believe in our product fully.

Q: Is it safe?

A: Absolutely. Organic Sulfur / MSM is a proven FOOD GRADE dietary supplement that is GMO Free, and Gluten Free. It has no set toxicity limits. We suggest starting with 1 level teaspoon in the morning and once in the evening. This will provide a truly therapeutic dose of Organic Sulfur to your body.

Note: Taking extremely large doses, (3+ Tablespoons or more) of Organic Sulfur can cause stomach upset and diarrhea. As well Sulfur can have slight blood thinning properties, so its best to take a few hours before or after meds.

If you are pregnant or are unsure based on pre-existing conditions and medications, always speak with your Doctor before trying any new supplement.

Q: Can I give it to my pets?

A: We encourage you to! With the store pet foods our pets eat today, their bodies are literally dying for access to Organic Sulfur. For dogs especially, with joint issues it is an amazing dietary supplement with very powerful results for their pain and well-being. We now offer a version specially blended for dogs, click here for our msm for dogs and cats.

Q: Are you easy to reach and give good customer service?

A: Our email is support[at]happybodystore.com or call us at 1.800.610.9210 if you have questions. We are at our customer service desks Monday to Friday between 10am – 4:30pm EST. We pride ourselves on excellent customer support.

Q:  What about shipping and returns?

A: We ship very fast. Our warehouse is just outside Los Angeles for US Orders, and Toronto for Canadian Orders. We ship 5 days a week using USPS, Fed Ex or UPS. It usually takes about 3 -5 business days to get your product.

Returns are easy. Just call or email us, we will then initiate your return, and refund process which takes about 7 – 12 business days to show up on your statement or PayPal account, once we receive and log your product back at our warehouse. Simple!


  1. Debbi EM, et al Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study . BMC Complement Altern Med. (2011)
  2.  El-Gindy A, et al Reflectance near-infrared spectroscopic method with Chemometric techniques for simultaneous determination of Chondroitin, glucosamine, and methyl sulfonyl methane . J AOAC Int. (2012)
  3.  Williams KI, Burstein SH, Layne DS Dimethyl sulfone: isolation from cows’ milk . Proc Soc Exp Biol Med. (1966)
  4.  Willemsen MA, et al Methylsulfonylmethane (MSM) ingestion causes a significant resonance in proton magnetic resonance spectra of brain and cerebrospinal fluid. Neuropediatrics. (2006)
  5.  Geba GP, et al Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial . JAMA. (2002)
  6.  Joung YH, et al MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs . PLoS One. (2012)
  7.  Nakhostin-Roohi B, et al Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men . J Pharm Pharmacol. (2011)
  8.  Zhang M, et al Topical metal chelation therapy ameliorates oxidation-induced toxicity in diabetic cataract . J Toxicol Environ Health A. (2011)
  9.  Klandorf H, et al Dimethyl sulfoxide modulation of diabetes onset in NOD mice . Diabetes. (1989)
  10.  Werchan PM, et al Right ventricular performance after monocrotaline-induced pulmonary hypertension . Am J Physiol. (1989)
  11.  Williams KI, Burstein SH, Layne DS Metabolism of dimethyl sulfide, dimethyl sulfoxide, and dimethyl sulfone in the rabbit . Arch Biochem Biophys. (1966)
  12.  GC-MS identification of dimethyl sulfone in cow’s milk and other livestock products
  13.  Cecil KM, et al Methylsulfonylmethane observed by in vivo proton magnetic resonance spectroscopy in a 5-year-old child with developmental disorder: effects of dietary supplementation . J Comput Assist Tomogr. (2002)
  14.  Parcell S Sulfur in human nutrition and applications in medicine . Altern Med Rev. (2002)
  15.  Yi HK, et al Expression of the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs) in human gastric cancer cells . Eur J Cancer. (2001)
  16.  Rogovin JL Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy . Toxicol Lett. (2002)
  17.  Apps P, Mmualefe L, McNutt JW Identification of volatiles from the secretions and excretions of African wild dogs (Lycaon pictus) . J Chem Ecol. (2012)
  18.  Jin HF, et al Effects of endogenous sulfur dioxide on monocrotaline-induced pulmonary hypertension in rats . Acta Pharmacol Sin. (2008)
  19.  Barmaki S, et al Effect of methylsulfonylmethane supplementation on exercise – Induced muscle damage and total antioxidant capacity . J Sports Med Phys Fitness. (2012)
  21.  Richmond VL Incorporation of methylsulfonylmethane sulfur into guinea pig serum proteins . Life Sci. (1986)
  22. Gumina S, et al Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: a prospective randomized study . Curr Med Res Opin. (2012)
  23.  Clark T, et al Why are dimethyl sulfoxide and dimethyl sulfone such good solvents . J Mol Model. (2008)
  24.  Smale BC, Lasater NJ, Hunter BT Fate and metabolism of dimethyl sulfoxide in agricultural crops . Ann N Y Acad Sci. (1975)
  25.  Song Y, et al Investigation of iminosulfuranes as novel transdermal penetration enhancers: enhancement activity and cytotoxicity . Pharm Res. (2005)
  26.  Ben-Porath I, Weinberg RA The signals and pathways activating cellular senescence . Int J Biochem Cell Biol. (2005)
  27.  Burger BV, et al Elemental sulfur identified in urine of cheetah, Acinonyx jubatus . J Chem Ecol. (2006)
  28.  Hwang PH, et al PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells . Exp Mol Med. (2005)
  29.  Egorin MJ, et al Plasma concentrations and pharmacokinetics of dimethylsulfoxide and its metabolites in patients undergoing peripheral-blood stem-cell transplants . J Clin Oncol. (1998)
  30.  Mohammadi S, et al Protective effects of methylsulfonylmethane on hemodynamics and oxidative stress in monocrotaline-induced pulmonary hypertensive rats .Adv Pharmacol Sci. (2012)
  31.  Kurihara-Bergstrom T, Flynn GL, Higuchi WI Physicochemical study of percutaneous absorption enhancement by dimethyl sulfoxide: kinetic and thermodynamic determinants of dimethyl sulfoxide mediated mass transfer of alkanols . J Pharm Sci. (1986)
  32.  Amirshahrokhi K, Bohlooli S, Chinifroush MM The effect of methylsulfonylmethane on the experimental colitis in the rat . Toxicol Appl Pharmacol. (2011)
  33.  Brayton CF Dimethyl sulfoxide (DMSO): a review . Cornell Vet. (1986)
  34.  Pearson TW, Dawson HJ, Lackey HB Natural occurring levels of dimethyl sulfoxide in selected fruits, vegetables, grains, and beverages . J Agric Food Chem. (1981)
  35.  Mode of action of penetration enhancers in human skin
  36.  Sweeney TM, Downes AM, Matoltsy AG The effect of dimethyl sulfoxide on the epidermal water barrier . J Invest Dermatol. (1966)
  37.  Feng L, et al Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide . J Clin Invest. (1995)
  38.  Lleonart ME, Artero-Castro A, Kondoh H Senescence induction; a possible cancer therapy . Mol Cancer. (2009)
  39.  Kim YH, et al The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages . Biol Pharm Bull. (2009)

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